Library / English Dictionary

    HISTAMINE

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Amine formed from histidine that stimulates gastric secretions and dilates blood vessels; released by the human immune system during allergic reactionsplay

    Classified under:

    Nouns denoting body parts

    Hypernyms ("histamine" is a kind of...):

    amine; aminoalkane (a compound derived from ammonia by replacing hydrogen atoms by univalent hydrocarbon radicals)

    Credits

     Context examples: 

    This agent exhibits no anticholinergic activities and does not antagonize histamine H2 receptors.

    (Omeprazole, NCI Thesaurus)

    Pheniramine maleate binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide.

    (Pheniramine Maleate, NCI Thesaurus)

    These histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles.

    (Antazoline, NCI Thesaurus)

    Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells.

    (Amlexanox, NCI Thesaurus)

    Phenyltoloxamine blocks H1 histamine receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide.

    (Phenyltoloxamine, NCI Thesaurus)

    Perphenazine appears to exert its antiemetic activity by blocking the dopamine and histamine-1 receptor in the CTZ thereby relieving nausea and vomiting in the brain.

    (Perphenazine, NCI Thesaurus)

    The phosphate salt of antazoline, an ethylenediamine derivative with histamine H1 antagonistic and sedative properties.

    (Antazoline Phosphate, NCI Thesaurus)

    In addition, orphenadrine exerts antagonistic effects on histamine H1 receptors.

    (Orphenadrine, NCI Thesaurus)

    A type of drug that blocks the action of histamines, which can cause fever, itching, sneezing, a runny nose, and watery eyes.

    (Antihistamine, NCI Dictionary)

    This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process.

    (Pemirolast Potassium, NCI Thesaurus)


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