Health / Medical Topics

    13-Deoxydoxorubicin

    Definition 1

    An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic. (NCI Thesaurus)

    Definition 2

    An anticancer drug that belongs to the family of drugs called antitumor antibiotics. It is an anthracycline. (NCI Dictionary)




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