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72
I. (adjective)
Sense 1
Meaning:
Being two more than seventy
Synonyms:
72; lxxii; seventy-two
Classified under:
Similar:
cardinal (being or denoting a numerical quantity but not order)
Context examples:
Human DTL wild-type allele is located in the vicinity of 1q32 and is approximately 72 kb in length.
(DTL wt Allele, NCI Thesaurus)
Delayed hypersensitivity reaction (DTH) - type IV reaction, an inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign.
(Delayed-Type Hypersensitivity, NCI Thesaurus)
Human FGF2 wild-type allele is located within 4q26-q27 and is approximately 72 kb in length.
(FGF2 wt Allele, NCI Thesaurus)
Ganetespib binds to and inhibits Hsp90, resulting in the proteasomal degradation of oncogenic client proteins, the inhibition of cell proliferation and the elevation of heat shock protein 72 (Hsp72); it may inhibit the activity of multiple kinases, such as c-Kit, EGFR, and Bcr-Abl, which as client proteins depend on functional HsP90 for maintenance.
(Ganetespib, NCI Thesaurus)
In addition, H1-infected tumor cells strongly induce the release of the inducible heat shock protein 72 (Hsp72i), which chaperone tumor associated antigens in the H1-mediated tumor lysates and may activate antigen presenting cells (APCs), thereby leading to antitumor immune responses.
(Parvovirus H-1, NCI Thesaurus)
Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock protein 72 (Hsp72) in a wide range of human tumor cell lines.
(Hsp90 Inhibitor AUY922, NCI Thesaurus)
Utilizing CHCC49 antibodies avoid anti-mouse immune response in human, which occured with the use of mouse CC49 antibody, but still exhibit the same affinity for human TAG-72 antigen, thereby resulting in strong radioimaging activity when linked to a radioisotope.
(Chimeric Antibody CHCC49, NCI Thesaurus)
Monoclonal antibody CC49-deltaCH2 targets the tumor-associated glycoprotein 72 (TAG-72) that is expressed by a wide range of human neoplasms including colorectal, gastric, pancreatic, ovarian, endometrial, breast, non-small cell lung, and prostate cancers.
(Iodine I 131 Monoclonal Antibody CC49-deltaCH2, NCI Thesaurus)
