| Library / English Dictionary |
ABC
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The elementary stages of any subject (usually plural)
Example:
he mastered only the rudiments of geometry
Synonyms:
ABC; ABC's; ABCs; alphabet; first principles; rudiments
Classified under:
Nouns denoting cognitive processes and contents
Hypernyms ("ABC" is a kind of...):
basic principle; basics; bedrock; fundamental principle; fundamentals (principles from which other truths can be derived)
Domain usage:
plural; plural form (the form of a word that is used to denote more than one)
Context examples:
ABC Transporter Inhibition involves interference with, or restraint of, the activities of cell membrane glycoproteins selectively permeable to P-glycoprotein substrates.
(ABC Transporter Inhibition, NCI Thesaurus)
Developed in partnership with the Juazeiro do Norte College, the ABC Medical School, and Oxford Brookes University, in the UK, the research found the association beneficial in 37 patients.
(Music believed to boost hypertension treatment, Agenciabrasil/EBC)
ABC transporters consist of two integral membrane proteins (permeases) each having six transmembrane segments, two peripheral membrane proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein.
(ABC Transporter, NCI Thesaurus)
It was featured on a program called Stargazing Live on the Australia Broadcasting Corporation (ABC).
(Multi-planet System Found Through Crowdsourcing, NASA)
Human ABCB1-C allele is the wild-type form of the human ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) gene (ABC gene family), located at located at 7q21.1, which encodes multidrug resistance protein 1.
(ABCB1 1 Allele, NCI Thesaurus)
ABC Transporter Binding involves temporary non-covalent interaction of a molecule through intermolecular physical forces of attraction with the ABC Transporter complex to move the substrate across the plasma cell membrane against a concentration gradient.
(ABC Transporter Binding, NCI Thesaurus)
In addition, because this agent is not a substrate for several types of multidrug resistance (MDR) ABC superfamily transporters, such as P-glycoprotein 1 (MDR-1), multidrug resistance-associated protein 1 (MRP1), and breast cancer resistance protein 1 (BCRP1/ABCG2), it may be useful in treating MDR tumors that express these particular MDR efflux pumps.
(Apoptosis Inducer MPC-2130, NCI Thesaurus)
ABC proteins transport various molecules across extra- and intra-cellular membranes.
(ATP-Binding Cassette, Sub-Family B, Member 6, NCI Thesaurus)
The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein.
(ABC Transporter Pathway, NCI Thesaurus/KEGG)
ATP-Binding Cassette, Sub-Family B, Member 6, encoded by the ABCB6 gene, is a membrane-associated protein of the superfamily of ATP-binding cassette (ABC) transporters.
(ATP-Binding Cassette, Sub-Family B, Member 6, NCI Thesaurus)
