ABCB1 wt Allele

Human ABCB1 wild-type allele is located in the vicinity of 7q21.1 and is approximately 210 kb in length. This allele, which encodes multidrug resistance protein 1, is involved in transmembrane transport. Amplification of the ABCB1 gene is a major determinant in the development of multi-drug resistance, which decreases the effectiveness of many chemotherapeutic agents used in cancer treatment. (NCI Thesaurus)

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ABCB1 Gene

This gene plays a role in multi-drug resistance and is involved in blood-brain barrier transport.

ABCB1 2 Allele

Human ABCB1-T allele is a variant form of the human ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) gene, located at 7q21.1,…

ABCB1 1 Allele

Human ABCB1-C allele is the wild-type form of the human ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) gene (ABC gene family),…

ABCA5 wt Allele

Human ABCA5 wild-type allele is located in the vicinity of 17q24.3 and is approximately 83 kb in length. This allele, which encodes…

ABCA5 Gene

This gene is involved in both ATP binding and catabolism.

ABCA2 wt Allele

Human ABCA2 wild-type allele is located in the vicinity of 9q34 and is approximately 22 kb in length. This allele, which encodes…