Health / Medical Topics

    Aberrant Crypt Focus

    Definition 1

    A larger than normal, microscopically elevated colonic crypt that may contain dysplastic epithelium. It is considered as a possible precursor of colonic adenoma and carcinoma. (NCI Thesaurus)

    Definition 2

    Clusters of abnormal tube-like glands in the lining of the colon and rectum. ACF form before colorectal polyps and are one of the earliest changes that can be seen in the colon that may lead to cancer. (NCI Dictionary)




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