Library / English Dictionary

ADENOSINE DEAMINASE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

An enzyme found in mammals that can catalyze the deamination of adenosine into inosine and ammonia

Example:

the gene encoding ADA was one of the earlier human genes to be isolated and cloned for study

Synonyms:

ADA; adenosine deaminase

Classified under:

Nouns denoting substances

Hypernyms ("adenosine deaminase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

Credits

 Context examples: 

A preparation of autologous, CD34-positive stem/progenitor cells transduced with a lentrivral vector encoding the human adenosine deaminase (ADA) gene under the control of the human elongation factor alpha short promoter (EFS), with potential to restore ADA expression and function.

(EFS-ADA Lentiviral Vector-transduced CD34-positive Autologous Lymphocytes, NCI Thesaurus)

Certain allelic variants of the ADA gene are associated with adenosine deaminase deficiency which, in some cases, causes autosomal recessive severe combined immunodeficiency.

(ADA wt Allele, NCI Thesaurus)