AICDA wt Allele

Human AICDA wild-type allele is located in the vicinity of 12p13 and is approximately 11 kb in length. This allele, which encodes activation-induced cytidine deaminase protein, is involved in both DNA methylation and B-cell differentiation. Mutation of the gene is associated with immunodeficiency with hyper-IgM type 2. (NCI Thesaurus)

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AICDA Gene

This gene plays a role in both class-switch recombination in B-lymphocytes and cytidine deamination.

Aicardi Syndrome

A sporadic genetic syndrome characterized by agenesis of the corpus callosum, infantile spasms, and chorioretinal lacunae. It is associated with the…

AI Regimen

A regimen consisting of doxorubicin and ifosfamide used for the treatment of unresectable soft tissue sarcoma.

AHR wt Allele

Human AHR wild-type allele is located in the vicinity of 7p15 and is approximately 48 kb in length. This allele, which encodes…

AHR Signal Transduction Pathway

The Ah receptor, bHLH/PAS transcription factor, upon binding of an agonist such as 2,3,7,8-tetrachlorodibenzo-p-dioxin translocates into the nucleus and heterodimerizes with the…

AHR Gene

This gene is involved in the regulation of xenobiotic-metabolizing enzymes.