Health / Medical Topics

    AKR1C2 wt Allele

    Human AKR1C2 wild-type allele is located within 10p15-p14 and is approximately 30 kb in length. This allele, which encodes aldo-keto reductase family 1 member C2 protein, is involved in the metabolism of steroid hormones and the inactivation of androgens. Mutations in this gene are associated with 46XY sex reversal 8. (NCI Thesaurus)




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    Human AKR1C1 wild-type allele is located within 10p15-p14 and is approximately 91 kb in length. This allele, which encodes aldo-keto reductase family…
    This gene is involved in the metabolism of aldehydes and ketones.
    Human AKR1A1 wild-type allele is located within 1p33-p32 and is approximately 20 kb in length. This allele, which encodes alcohol dehydrogenase [NADP(+)]…
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    Originally disseminated by Detweiler and carried by Furth (1928-1936) and the Rockefeller Institute for subsequent generations. The AKR mouse has an albino…

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