Library / English Dictionary

ALLELE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

(genetics) either of a pair (or series) of alternative forms of a gene that can occupy the same locus on a particular chromosome and that control the same character

Example:

some alleles are dominant over others

Synonyms:

allele; allelomorph

Classified under:

Nouns denoting body parts

Hypernyms ("allele" is a kind of...):

cistron; factor; gene ((genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity)

Domain category:

genetic science; genetics (the branch of biology that studies heredity and variation in organisms)

Hyponyms (each of the following is a kind of "allele"):

dominant; dominant allele (an allele that produces the same phenotype whether its paired allele is identical or different)

recessive; recessive allele (an allele that produces its characteristic phenotype only when its paired allele is identical)

Derivation:

allelic (of or relating to alleles)

Credits

 Context examples: 

This allele, which encodes mitofusin-2 protein, plays a role in both GTP hydrolysis and mitochondrial fusion.

(MFN2 wt Allele, NCI Thesaurus)

Human MFNG wild-type allele is located in the vicinity of 22q12 and is approximately 17 kb in length.

(MFNG wt Allele, NCI Thesaurus)

Human MGAT4C wild-type allele is located in the vicinity of 12q21 and is approximately 860 kb in length.

(MGAT4C wt Allele, NCI Thesaurus)

This allele, which encodes lactadherin, is involved in apoptosis and integrin interactions.

(MFGE8 wt Allele, NCI Thesaurus)

This allele, which encodes proto-oncogene tyrosine-protein kinase MER protein, plays a role in tissue homeostasis and receptor signaling.

(MERTK wt Allele, NCI Thesaurus)

Human MESDC2 wild-type allele is located in the vicinity of 15q13 and is approximately 38 kb in length.

(MESDC2 wt Allele, NCI Thesaurus)

This allele, which encodes hepatocyte growth factor receptor protein, plays a role in the regulation of cellular tyrosine-kinase activity.

(MET wt Allele, NCI Thesaurus)

This allele, which encodes multidrug resistance-associated protein 4, is involved in ATP hydrolysis, anion transport and platelet activation.

(ABCC4 wt Allele, NCI Thesaurus)

Human AATF wild-type allele is located within 17q11.2-q12 and is approximately 108 kb in length.

(AATF wt Allele, NCI Thesaurus)

This allele, which encodes alpha-2-macroglobulin protein, plays a role in various processes as a protease inhibitor.

(A2M wt Allele, NCI Thesaurus)