Amantadine

A synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect against the influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the release of infectious viral nucleic acids into host cells. Furthermore, this agent prevents virus assembly during virus replication. Amantadine exerts its antiparkinsonian effects by stimulating the release of dopamine from striatal dopaminergic nerve terminals and inhibiting its pre-synaptic reuptake. This agent may also exert some anticholinergic effect through inhibition of N-methyl-D-aspartic acid (NMDA) receptor-mediated stimulation of acetylcholine, resulting in antihyperalgesia. (NCI Thesaurus)

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Amalgam

An alloy, typically a mix of silver, tin, and mercury, used in direct dental restorations.

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A retinal neuron that lacks large axons, having only processes that resemble dendrites.

AMACR wt Allele

Human AMACR wild-type allele is located within 5p13.2-q11.1 and is approximately 21 kb in length. This allele, which encodes alpha-methylacyl-CoA racemase protein,…