Angiosarcoma

Pronunciation

Definition 1

A type of cancer that begins in the cells that line blood vessels or lymph vessels. Cancer that begins in blood vessels is called hemangiosarcoma. Cancer that begins in lymph vessels is called lymphangiosarcoma. (NCI Dictionary)

Definition 2

A malignant tumor arising from the endothelial cells of the blood vessels. Microscopically, it is characterized by frequently open vascular anastomosing and branching channels. The malignant cells that line the vascular channels are spindle or epithelioid and often display hyperchromatic nuclei. Angiosarcomas most frequently occur in the skin and breast. Patients with long-standing lymphedema are at increased risk of developing angiosarcoma. (NCI Thesaurus)

Definition 3

A malignant vascular neoplasm arising from endothelial cells. (NCI Thesaurus/CDISC)

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