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    ANGIOTENSIN I

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    A physiologically inactive form of angiotensin that is the precursor to angiotensin IIplay

    Classified under:

    Nouns denoting man-made objects

    Hypernyms ("angiotensin I" is a kind of...):

    angiotensin; angiotonin; Hypertensin (any of several vasoconstrictor substances (trade name Hypertensin) that cause narrowing of blood vessels)

    Credits

     Context examples: 

    Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

    (Enalapril, NCI Thesaurus)

    Idrapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

    (Idrapril, NCI Thesaurus)

    By competing with angiotensin I for ACE, deserpidine blocks the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor.

    (Deserpidine, NCI Thesaurus)

    This protein plays a role in the hydrolysis of angiotensin I to form angiotensin II and the solubilization of glycophophoinositol-anchored proteins from the plasma membrane.

    (Angiotensin-Converting Enzyme, NCI Thesaurus)

    The determination of the amount of angiotensin I hormone present in a sample.

    (Angiotensin I Measurement, NCI Thesaurus)

    Aliskiren selectively binds to the S3 sub-pocket of renin, an enzyme in the renin-angiotensin-aldosterone system (RAAS) that is responsible for converting angiotensinogen to angiotensin I (AT I).

    (Aliskiren, NCI Thesaurus)

    As a prodrug, alacepril is rapidly metabolized to captopril; captopril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

    (Alacepril, NCI Thesaurus)

    Angiotensinogen is digested by renin to produce angiotensin I (AGT I).

    (Angiotensin-converting Enzyme 2 Pathway, NCI Thesaurus/BIOCARTA)

    A measurement of the angiotensin I hormone in a biological specimen.

    (Angiotensin I Measurement, NCI Thesaurus/CDISC)

    As a prodrug cilazapril is rapidly metabolized in the liver to cilazaprilat; cilazaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

    (Cilazapril Anhydrous, NCI Thesaurus)


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