ANP32D Protein

Encoded by human ANP32D Gene, 131-amino acid 14.8 kD PP32R2 Protein (PP32 Family) shares approximately 90% amino acid sequence identity with tumor suppressor PP32 and PP32R1. PP32 can inhibit several types of cancers, including prostate and breast cancers. PP32R2 and PP32R1 are tumorigenic. Amino acids 150-174 of PP32 are responsible for its tumor suppressor function and are a region of divergence with PP32R1. Alternative use of PP32, PP32R1, and PP32R2 may modulate the oncogenic potential of human prostate cancer. PP32R2 is expressed in prostate cancer. (from SWISS-PROT, OMIM, and NCI) (NCI Thesaurus)

YOU MAY ALSO LIKE

ANP32D Gene

This gene plays a prominent role in tumor suppression.

ANP32C wt Allele

Human ANP32C wild-type allele is located in the vicinity of 4q32.3 and is approximately 1 kbin length. This allele, which encodes acidic…

ANP32C Protein

Encoded by human ANP32C Gene, 234-amino acid 27 kD PP32R1 Protein (PP32 Family) shares approximately 90% amino acid sequence identity with tumor…

ANP32C Gene

This gene is involved in tumor suppression.

ANP32B wt Allele

Human ANP32B wild-type allele is located in the vicinity of 9q22.32 and is approximately 33 kb in length. This allele, which encodes…

ANP32B Gene

This gene plays a regulatory role in the propagation of pro-apoptotic events.