Anti-CEA BiTE Monoclonal Antibody MEDI-565

A recombinant, proprietary bispecific T-cell engagers (BiTE) antibody directed against human carcinoembryonic antigen (CEA), with potential immunostimulating and antineoplastic activities. Anti-CEA BiTE monoclonal antibody MEDI-565 possesses two antigen-recognition sites, one for CEA and one for the CD3 complex, a group of T cell surface glycoproteins that complex with the T cell receptor (TCR). This bispecific monoclonal antibody brings CEA-expressing tumor cells and cytotoxic T lymphocytes (CTLs) and helper T lymphocytes (HTLs) together, which may result in the CTL- and HTL-mediated cell death of CEA-expressing cells. CEA, a tumor associated antigen, is overexpressed in many cancer types, including gastrointestinal, breast, non-small cell lung, and thyroid cancers. (NCI Thesaurus)

YOU MAY ALSO LIKE

anti-CEA antibody

An antibody against carcinoembryonic antigen (CEA), a protein present on certain types of cancer cells.

Anti-CD8 Monoclonal Antibody

Any monoclonal antibody directed against the cell surface glycoprotein CD8, regardless of the antibody type.

Anti-CD79B Monoclonal Antibody-MMAE Conjugate DCDS4501A

An antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against B-cell antigen receptor complex-associated protein beta chain (CD79B) conjugated, via a…

Anti-CD70 Monoclonal Antibody MDX-1411

A glycoengineered, fully humanized IgG1 monoclonal antibody directed against the extracellular domain of the human CD70 molecule with potential antineoplastic activity. Anti-CD70…

Anti-CD70 Monoclonal Antibody ARGX-110

A defucosylated, humanized IgG1 monoclonal antibody directed against the extracellular domain of the human CD70 molecule with potential antineoplastic activity. Upon administration,…

Anti-CD70 Antibody-Drug Conjugate MDX-1203

An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody, directed against the extracellular domain of the human CD70 molecule, conjugated to…