Health / Medical Topics

    BCR Protein

    The 160 kD BCR phosphoprotein exhibits a unique serine/threonine kinase activity, at least two SH2 binding sites, and a C-terminal GTPase activating domain for p21(rac). The Philadelphia translocation produces a BCR-ABL1 chimeric product required for induction and maintenance of leukemia. (from OMIM 151410 and NCI) (NCI Thesaurus)




    YOU MAY ALSO LIKE

    This gene plays a role in signal transduction.
    BCR Downstream Signaling 1, encoded by BRDG1 gene, functions as a docking protein acting downstream of Tec tyrosine kinase in B cell…
    Human BCPR wild-type allele is located in the vicinity of 5p13.3 and the length of the gene is currently unknown. This allele,…
    Encoded by human BCPR Gene, BCPR Protein appears to be associated with expression of p53, perhaps regulating its expression. Lesions of…
    This gene is involved in tumor suppression.
    Human BCOR wild-type allele is located in the vicinity of Xp11.4 and is approximately 128 kb in length. This allele, which encodes…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact