Benign Giant Cell Tumor of Bone

Definition 1

A benign, locally aggressive bone tumor, usually arising in the end of long bones or the vertebrae. The tumor is composed of round or oval mononuclear cells and uniformly distributed osteoclast-like giant cells. Clinical presentation includes pain, edema, and decrease range of motion in the affected joint. (NCI Thesaurus)

Definition 2

A benign neoplasm of bone comprised of giant cells (osteoclast-like) and mononuclear cells. (NCI Thesaurus/CDISC)

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