| Health / Medical Topics |
bHLH-Zip Domain
Tripartite DNA binding domain containing a basic region, a helix-loop-helix, and a leucine zipper. (NCI Thesaurus)
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bHLH class proteins are sequence-specific DNA-binding proteins that contain a conserved 50-amino acid HLH domain consisting of two alpha-helices separated by a…
The bHLH domain is a bipartite DNA-binding domain containing a basic region upstream of an amphipathic helix-loop-helix region. The basic region interacts…
BH4 is present only in the amino-terminal regions of pro-survival family bcl-2 members and is essential for the anti-apoptotic function, although deletion…
BH3-interacting domain death agonist (195 aa, ~22 kDa) is encoded by the human BID gene. This protein plays a role in the…
The alpha-helical BH3 domain (9 amino acids) represents a minimal death domain and is essential for the activity of pro-apoptotic members of…
Found in proteins that regulate apoptosis, conserved a-helix BCL-2 Homology (BH1-4) Domains are critical to protein apoptotic function and the protein ability…
