Health / Medical Topics

    BIBX 1382

    Definition 1

    A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called epidermal growth factor receptor (EGFR) inhibitors. (NCI Dictionary)

    Definition 2

    A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation. (NCI Thesaurus)

    Definition 3

    A drug that may inhibit tumor cells from multiplying. It is being studied for its ability to treat cancer. (NCI Dictionary)




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