BRCA2

A gene on chromosome 13 that normally helps to suppress cell growth. A person who inherits certain mutations (changes) in a BRCA2 gene has a higher risk of getting breast, ovarian, prostate, and other types of cancer. (NCI Dictionary)

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BRCA1-associated RING domain protein 1 (777 aa, ~87 kDa) is encoded by the human BARD1 gene. This protein plays a role in…

BRCA1-A Complex Subunit Abraxas

BRCA1-A complex subunit Abraxas (409 aa, ~67 kDa) is encoded by the human FAM175A gene. This protein is involved in both DNA…

BRCA1 wt Allele

Human BRCA1 wild-type allele is located within 17q21 and is approximately 81 kb in length. This allele, which encodes breast cancer type…

BRCA1 Syndrome

An autosomal dominant inherited syndrome caused by mutations in the BRCA1 gene. Patients are at high risk of developing breast cancer, ovarian…

BRCA1 Gene Mutation

A mutation that is typically a heritable, permanent change in the nucleotide sequence of the BRCA1 gene. Single nucleotide substitutions and small…

BRCA1 Gene

This gene plays a role in cell cycle control, regulation of transcription and the maintenance of genomic stability. It is also involved…