Broccoli sprout extract

Pronunciation

Definition 1

A substance being studied in the prevention of cancer. Broccoli sprout extract comes from newly sprouted broccoli. It causes cells to make enzymes that may protect them against cancer-causing toxins in the body, and it may also block the growth of cancer cells. (NCI Dictionary)

Definition 2

A cruciferous vegetable extract with potential chemopreventive activities. Broccoli sprout extract contains a high amount of sulforaphane, a naturally occurring isothiocyanate. Sulforaphane activates the transcription factor NF-E2-related factor 2 (Nrf2), a member of the basic leucine zipper family, which binds to and activates antioxidant-response elements (AREs). Subsequently, activated AREs mediate the transcription of antioxidant enzymes (particularly glutathione-S-transferase and quinone oxidoreductase), resulting in the detoxification of highly reactive carcinogens. AREs are cis-acting regulatory enhancer elements found in the 5' flanking region of many phase II detoxification enzymes. (NCI Thesaurus)

YOU MAY ALSO LIKE

Broca's Aphasia

An aphasia characterized by impairment of expressive language (speech, writing, signs) and relative preservation of receptive language abilities (i.e., comprehension). This condition…

Brobactam

A synthetic inhibitor of beta-lactamases produced by both gram-positive and gram-negative bacteria. Brobactam potentiates the antibacterial activity of ampicillin against a wide…

Broad-Spectrum Human Papillomavirus Vaccine V505

A non-infectious recombinant cancer vaccine prepared from the human papillomavirus (HPV) with potential immunoprophylactic activity. Vaccination with broad-spectrum human papillomavirus vaccine V505…

Broad Ligament

A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis.

Broad Casts Measurement

The determination of the amount of urinary broad (waxy) casts present in a sample.

Broad

Very large in expanse or scope; having great extent from one side to the other.