| Health / Medical Topics |
BTK wt Allele
Human BTK wild-type allele is located within Xq21.33-q22 and is approximately 37 kb in length. This allele, which encodes tyrosine-protein kinase BTK protein, plays a role in the mediation of signal transduction during B-cell development. Mutation of the gene is associated with X-linked agammaglobulinemia type 1. (NCI Thesaurus)
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