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CALCIUM ION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Ion of calcium; a factor in the clotting of blood
Synonyms:
calcium ion; factor IV
Classified under:
Hypernyms ("calcium ion" is a kind of...):
atomic number 20; Ca; calcium (a white metallic element that burns with a brilliant light; the fifth most abundant element in the earth's crust; an important component of most plants and animals)
clotting factor; coagulation factor (any of the factors in the blood whose actions are essential for blood coagulation)
Context examples:
Cadmium can enter cells through calcium ion channels and once in cells affects calcium release by the ER.
(Cadmium Induction Pathway, NCI Thesaurus/BIOCARTA)
Calcium Binding consists of a biophysical interaction between one or more calcium ion(s) and a biological molecule, such as a protein.
(Calcium Binding, NCI Thesaurus)
Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vascular smooth muscle, thereby dilating coronary arteries and peripheral arterioles.
(Isradipine, NCI Thesaurus)
This agent interferes with mediators release from mast cells either by inhibiting calcium ion influx across mast cell/basophil plasma membrane or by inhibiting intracellular calcium ion release within the cells.
(Fexofenadine, NCI Thesaurus)
The CD20 antigen, a non-glycosylated cell surface phosphoprotein that acts as a calcium ion channel, is found on over 90% of B-cells, B-cell lymphomas, and other lymphoid tumor cells of B-cell origin; it plays an important role in B-cell functioning.
(Ocrelizumab, NCI Thesaurus)
The CD20 antigen, found on over 90% of B cells, B cell lymphomas, and other B cells of lymphoid tumors of B cell origin, is a non-glycosylated cell surface phosphoprotein that acts a calcium ion channel; it is exclusively expressed on B cells during most stages of B cell development.
(Ofatumumab, NCI Thesaurus)
When cross-linked by secondary anti-mouse antibodies or Fc receptor-bearing cells, MOAB 1F5 may induce activation of B-cell protein tyrosine kinases, increases in B-cell intracellular calcium ion concentrations, and B-cell caspase activation, resulting in apoptosis of B cells expressing CD20.
(Monoclonal Antibody 1F5, NCI Thesaurus)
As a result this agent interferes with mediator release from mast cells either by inhibiting calcium ion influx across mast cell/basophil plasma membrane or by inhibiting intracellular calcium ion release within the cells.
(Emedastine, NCI Thesaurus)
Ammonium trichlorotellurate induces production of colony stimulating factor (CSF), interleukin-2 (IL-2), and IL-2 receptors by increasing the calcium ion influx through the cell membrane and subsequently exerts its immunostimulatory effects through the CSF-mediated increase in macrophage/granulocytes.
(Ammonium Trichlorotellurate, NCI Thesaurus)
Calcium Binding Proteins typically belong to the same evolutionary family and often share an EF-hand calcium-binding domain that consists of a 12 residue loop flanked on both sides by a 12 residue alpha-helical domain; the calcium ion is coordinated with oxygen of Glu or Asp residues in a pentagonal bipyramidal configuration.
(Calcium Binding Protein, NCI Thesaurus)
