| Health / Medical Topics |
Candesartan
A synthetic, benzimidazole-derived angiotensin II receptor antagonist prodrug with antihypertensive activity. Candesartan selectively competes with angiotensin II for the binding of the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation. In addition, antagonism of AT1 in the adrenal gland inhibits angiotensin II-stimulated aldosterone synthesis and secretion by the adrenal cortex; sodium and water excretion increase, followed by a reduction in plasma volume and blood pressure. (NCI Thesaurus)
YOU MAY ALSO LIKE
A unit of luminous intensity, one of the seven base units of the International System of Units (Systeme International d'Unites, SI). It…
CancerVax is an allogenic polyvalent vaccine composed of irradiated but viable cells from three melanoma cell lines and Bacille Calmette-Guerin (BCG). The…
A web site (http://cancertrials.nci.nih.gov/) which acts as NCI's online gateway to clinical trials resources. It integrates information about clinical trials participation (including…
A web site (http://cancernet.nci.nih.gov/) which hosts NCI's searchable clinical trials database containing information on over 1,800 active clinical trials.
CANCERLIT is an NCI bibliographic database of more than 1.4 million records of cancer literature published in the past 30 years. It…
Includes NCI information about cancer treatment, screening, prevention, and supportive care. Can be accessed by telephone with information returned by…
