Cardiotrophin 1

Cardiotrophin 1 was cloned via its ability to potently induce cardiac myocyte hypertrophy in vitro. It is a member of the family of cytokines that includes leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and interleukin 6 (IL6). Several members of this family that are known to signal through the transmembrane protein gp130 stimulate cardiac myocyte hypertrophy, like cardiotrophin 1, suggesting that the gp130 signaling pathway may play a role in cardiac hypertrophy. (NCI Thesaurus/from OMIM)

YOU MAY ALSO LIKE

Cardiotoxicity

Toxicity that affects the heart.

Cardiotonic Agent

any agent having a favorable effect on the function of the heart.

Cardiotocography

The monitoring of both maternal uterine contractions and fetal heart rate during the process of labor and delivery.

Cardiorespiratory Fitness

The ability of the heart and lungs to deliver blood and oxygen to the tissues during aerobic activity. It is a general…

Cardiopulmonary resuscitation

An emergency procedure used to restart a person’s heartbeat and breathing after one or both have stopped. It involves giving strong, rapid…

Cardiopulmonary Physiology

Study of the functions and activities of the cardiopulmonary system as a whole or of any of its parts.