Health / Medical Topics

    Carzelesin

    Pronunciation

    Definition 1

    An anticancer drug that belongs to the family of drugs called alkylating agents. (NCI Dictionary)

    Definition 2

    A cyclopropylpyrroloindole prodrug analogue and DNA minor groove binding agent, with antineoplastic activity. After hydrolysis, the cyclopropyl group of carzelesin alkylates N3-adenine in a sequence-selective fashion. This results in tumor growth inhibition. (NCI Thesaurus)




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