CBFB wt Allele

Human CBFB wild-type allele is located in the vicinity of 16q22.1 and is approximately 72 kb in length. This allele, which encodes core-binding factor subunit beta protein, plays a role in the mediation of transcription. Acute myeloid leukemia of the M4Eo subtype is linked to the occurrence of a chromosomal inversion inv(16)(p13;q22), which fuses this gene to the MYH11 gene. (NCI Thesaurus)

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CBFB Gene

This gene is involved in hematopoiesis and osteogenesis.

CBFA2T3/GLIS2 Fusion Protein

A fusion protein encoded by the CBFA2T3/GLIS2 fusion gene. This protein is comprised of the N-terminal TAFH domain of the protein CBFA2T3…

CBFA2T3/GLIS2 Fusion Gene

A fusion gene that results from a chromosomal translocation inv(16)(p13q24) which fuses either the first 10 or 11 exons of the CBFA2T3…

CBFA2T3 wt Allele

Human CBFA2T3 wild-type allele is located in the vicinity of 16q24 and is approximately 102 kb in length. This allele, which encodes…

CBFA2T3 Gene

This gene plays a role in transcriptional regulation.

CBFA2T2 wt Allele

Human CBFA2T2 wild-type allele is located in the vicinity of 20q11 and is approximately 160 kb in length. This allele, which encodes…