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CDC73 wt Allele
Human CDC73 wild-type allele is located in the vicinity of 1q25 and is approximately 132 kb in length. This allele, which encodes parafibromin protein, plays a role in the modulation of both RNA polymerase II-directed transcription and histone methylation. Hyperparathyroidism-jaw tumor syndrome is associated with mutations that result in truncation of this gene. (NCI Thesaurus)
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