Health / Medical Topics

    CDK4 wt Allele

    Human CDK4 wild-type allele is located within 12q14 and is approximately 4 kb in length. This allele, which encodes cyclin-dependent kinase 4 protein, is involved in the regulation of cell cycle progression from G1/S phase. Variant mutated alleles are associated with tumorigenesis for a variety of cancers. (NCI Thesaurus)




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