CDKL5 wt Allele

Human CDKL5 wild-type allele is located in the vicinity of Xp22 and is approximately 228 kb in length. This allele, which encodes cyclin-dependent kinase-like 5 protein, is involved in the mediation of protein phosphorylation. Translocations and mutations involving the gene are associated with X-linked infantile spasm syndrome 2. Rett syndrome also is associated with defects in the gene. (NCI Thesaurus)

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CDKL5 Gene

This gene plays a role in protein metabolism.

CDKL2 wt Allele

Human CDKL2 wild-type allele is located in the vicinity of 4q21.1 and is approximately 51 kb in length. This allele, which encodes…

CDKL2 Gene

This gene plays a role in signal transduction.

CDKI R547

An orally bioavailable diaminopyrimidine compound and a cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. CDKs are ATP-dependent serine/threonine kinases that are…

CDKI AT7519

An orally bioavailable small molecule with potential antineoplastic activity. AT7519M selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result…

CDK8 wt Allele

Human CDK8 wild-type allele is located in the vicinity of 13q12 and is approximately 151 kb in length. This allele, which encodes…