Health / Medical Topics

    CGNL1 wt Allele

    Human CGNL1 wild-type allele is located in the vicinity of 15q21.3 and is approximately 174 kb in length. This allele, which encodes cingulin-like protein 1, is involved in the formation of tight junctions. A chromosomal inversion that positions the CGNL1 gene promoter into a position close to the CYP19A1 gene coding region is associated with aromatase excess syndrome. (NCI Thesaurus)




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