Library / English Dictionary

CHELATE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions

Synonyms:

chelate; chelate compound

Classified under:

Nouns denoting substances

Hypernyms ("chelate" is a kind of...):

heterocycle; heterocyclic; heterocyclic compound (a compound containing a heterocyclic ring)

Derivation:

chelate (form a chelate, in chemistry)

 II. (adjective) 

Sense 1

Meaning:

Having or resembling chelae or claws

Classified under:

Relational adjectives (pertainyms)

Pertainym:

chela (a grasping structure on the limb of a crustacean or other arthropods)

Sense 2

Meaning:

Relating to or characterized by chelation

Synonyms:

chelate; chelated

Classified under:

Relational adjectives (pertainyms)

Pertainym:

chelation (the process of forming a ring by forming one or more hydrogen bonds)

 III. (verb) 

Sense 1

Meaning:

Form a chelate, in chemistry

Classified under:

Verbs of being, having, spatial relations

Hypernyms (to "chelate" is one way to...):

constitute; form; make (to compose or represent)

Sentence frame:

Something ----s

Derivation:

chelate (a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions)

chelation (the process of forming a ring by forming one or more hydrogen bonds)

chelation ((medicine) the process of removing a heavy metal from the bloodstream by means of a chelate as in treating lead or mercury poisoning)

Credits

 Context examples: 

A derivative of pyridoxyl ethyldiamine (PLED) and mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with antioxidant, metal chelating and potential chemoprotective activities.

(PLED-based MnSOD Mimetic, NCI Thesaurus)

Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis.

(Penicillamine, NCI Thesaurus)

A monoclonal antibody directed against the neurohormone bombesin that is conjugated to isothiocyanobenzyl diethylenetriaminepentaacetic acid (ITC-D), a bifunctional chelating agent that allows the antibody to be labeled with a metal species.

(MoAb Bombesin (ITC-D), NCI Thesaurus)

Nitrilotriacetic acid is mainly used as a chelating and eluting agent and is found in laundry detergents.

(Nitrilotriacetic Acid, NCI Thesaurus)

An iron-chelating agent that removes iron from tumors by inhibiting DNA synthesis and causing cancer cell death.

(Deferoxamine, NCI Dictionary)

Ammonium tetrathiomolybdate is a type of chelating agent and a type of antiangiogenesis agent.

(Ammonium tetrathiomolybdate, NCI Dictionary)

ATN-224 selectively chelates the copper ion in superoxide dismutase 1 (SOD1) in endothelial cells, thereby depleting SOD1 of copper and inhibiting its activity.

(Bis(choline)tetrathiomolybdate, NCI Thesaurus)

A combination agent composed of the benzo-poly-carbonic-acid polymer BP-Cx1 chelated to platinum with potential antineoplastic activity.

(BP-Cx1-Platinum Complex BP-C1, NCI Thesaurus)

In medicine, chelating agents are used to remove toxic metals from the body.

(Chelating agent, NCI Dictionary)

Inhibited by chelating agents; requires divalent cations for activity.

(Aryldialkylphosphatase, NCI Thesaurus)