| Health / Medical Topics |
Chemokine (C-C Motif) Ligand 4
MIP-1 beta chemokine is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating hematopoiesis. MIP-1 beta is induced rapidly after T-cell activation with phytohemagglutinin, B-cell activation with Staphylococcus aureus, and monocyte activation with lipopolysaccharide. It is predominantly synthesized by perforin-low memory CD8+ T-cells, a major non-cytotoxic population of CD8+ T-cells. (from OMIM 182284 and NCI) (NCI Thesaurus)
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