Chromogranin

Definition 1

Chromogranins are acidic secretory glycoproteins with a widespread but specific distribution in neuroendocrine tissues. The chromogranin family is heterogenous, consisting of propeptides such as chromogranin-A, chromogranin-B and secretogranin II, which can either elicit an effect themselves, or serve as precursors to a large number of peptides, which are biologically more active. (NCI Thesaurus)

Definition 2

any of a group of acidic polypeptides that are the soluble protein constituents of the secretory granules of the chromaffin cells of the adrenal medulla; they are also widely distributed in endocrine tissues and tumor cells. (NIH CRISP Thesaurus)

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