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CJD
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I. (noun)
Sense 1
Meaning:
Rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control
Synonyms:
CJD; Creutzfeldt-Jakob disease; Jakob-Creutzfeldt disease
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("CJD" is a kind of...):
brain disease; brain disorder; encephalopathy (any disorder or disease of the brain)
Context examples:
Also called: CJD, Jakob-Creutzfeldt Disease, Mad Cow Disease, BSE, Bovine Spongiform Encephalopathy, vCJD
(Creutzfeldt-Jakob Disease, NIH: National Institute of Neurological Disorders and Stroke)
Human prion diseases include fatal insomnia; kuru; Gerstmann-Straussler-Scheinker syndrome; and variant, familial and sporadic CJD.
(NIH scientists and collaborators find infectious prion protein in skin of CJD patients, National Institutes of Health)
The finding suggests that the eye may be a source for early CJD diagnosis and raises questions about the safety of routine eye exams and corneal transplants.
(Eyes of CJD patients show evidence of prions, National Institutes of Health)
Creutzfeldt-Jakob disease (CJD) is a rare, degenerative brain disorder.
(Creutzfeldt-Jakob Disease, NIH: National Institute of Neurological Disorders and Stroke)
The scientists noted that in the CJD group, the “seeding potential” for normal prion protein to convert to abnormal was 1,000 to 100,000 times lower in skin than brain tissue.
(NIH scientists and collaborators find infectious prion protein in skin of CJD patients, National Institutes of Health)
Previous studies have shown that the eyes of CJD patients contain infectious prions, though the distribution of prions among the various components of the eye was not known.
(Eyes of CJD patients show evidence of prions, National Institutes of Health)
Cattle can get a disease related to CJD called bovine spongiform encephalopathy (BSE) or "mad cow disease."
(Creutzfeldt-Jakob Disease, NIH: National Institute of Neurological Disorders and Stroke)
The scientists then exposed humanized laboratory mice to either brain or skin extracts from two of the CJD patients.
(NIH scientists and collaborators find infectious prion protein in skin of CJD patients, National Institutes of Health)
About 40 percent of sporadic CJD patients develop eye problems that could lead to an eye exam, meaning the potential exists for the contamination of eye exam equipment designed for repeat use.
(Eyes of CJD patients show evidence of prions, National Institutes of Health)
The three main categories of CJD are: • Sporadic CJD, which occurs for no known reason • Hereditary CJD, which runs in families • Acquired CJD, which occurs from contact with infected tissue, usually during a medical procedure
(Creutzfeldt-Jakob Disease, NIH: National Institute of Neurological Disorders and Stroke)
