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CLEARANCE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Permission to proceed
Example:
the plane was given clearance to land
Classified under:
Nouns denoting acts or actions
Hypernyms ("clearance" is a kind of...):
license; permission; permit (the act of giving a formal (usually written) authorization)
Derivation:
clear (grant authorization or clearance for)
Sense 2
Meaning:
The distance by which one thing clears another; the space between them
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("clearance" is a kind of...):
interval; separation (the distance between things)
Derivation:
clear (pass by, over, or under without making contact)
Sense 3
Meaning:
Vertical space available to allow easy passage under something
Synonyms:
Classified under:
Nouns denoting quantities and units of measure
Hypernyms ("clearance" is a kind of...):
elbow room; room; way (space for movement)
Context examples:
The advantage of using 8.2 Fab fragments over whole antibodies is that they have reduced immunogenicity, better penetration of tissues, rapid clearance from the body and that they do not induce precipitation.
(Monoclonal Antibody 8.2 F(ab), NCI Thesaurus)
The advantage of using MoAb 96.5 Fab fragments over whole antibodies is that they have reduced immunogenicity, better penetration of tissues, rapid clearance from the body and that they do not induce precipitation.
(Monoclonal Antibody 96.5 F(ab), NCI Thesaurus)
The ability to manipulate these properties facilitates a controlled, localized activation and clearance mechanism of diseased or abnormal cells.
(Nanobomb, NCI Thesaurus)
The total clearance of a substance from the blood minus the renal clearance divided by the weight.
(Nonrenal Clearance Normalized by WT, NCI Thesaurus)
This gene is involved in both drug metabolism and bilirubin clearance.
(NR1I3 Gene, NCI Thesaurus)
The PEG moiety lowers the clearance of interferon alpha, thereby extending the duration of its therapeutic effects, but may also reduce interferon-mediated stimulation of an immune response.
(Pegylated Interferon Alfa, NCI Thesaurus)
The PEG moiety lowers the clearance of interferon alpha-2b, thereby extending the duration of its therapeutic effects, but may also reduce the interferon-mediated stimulation of an immune response.
(Peginterferon alfa-2b, NCI Thesaurus)
Pegylation provides improved drug penetration into tumors and decreases drug clearance, thereby increasing the duration of therapeutic effects while lowering the toxicity profile.
(Pegylated Irinotecan, NCI Thesaurus)
Liposomal delivery of doxorubicin HCl improves drug penetration into tumors and decreases drug clearance, thereby increasing the duration of therapeutic drug effects.
(Pegylated Liposomal Doxorubicin Hydrochloride, NCI Thesaurus)
The PEG moiety inhibits proteolytic breakdown and clearance of AM0010, which prolongs its half-life, extends the duration of its therapeutic effects and allows less frequent dosing.
(Pegylated Recombinant Human Interleukin-10 AM0010, NCI Thesaurus)
