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COPOLYMER
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A polymer consisting of two or more different monomers
Classified under:
Hypernyms ("copolymer" is a kind of...):
polymer (a naturally occurring or synthetic compound consisting of large molecules made up of a linked series of repeated simple monomers)
Derivation:
copolymerise; copolymerize (polymerize together)
Context examples:
Several different classes and types of copolymers exist.
(Copolymerization, NCI Thesaurus)
The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone.
(Paclitaxel-loaded polymeric micelle, NCI Thesaurus)
Carbetimer (carboxyimamidate) is a low molecular weight derivatized copolymer of ethylene and maleic anhydride.
(Carbetimer, NCI Thesaurus)
A hydrochloride salt form of colestipol, a positively charged, non-digestible, triamine and epoxypropane copolymer anion-exchange resin that binds to bile acids in the intestine to form an insoluble complex, which is excreted in the feces.
(Colestipol Hydrochloride, NCI Thesaurus)
A synthetic polymer (copolymer of 1,3-bis(methylaminocarboxyl)-2-methylenepropanecarbamate and N-vinyl pyrrolidone) of low molecular weight which acts as a nonspecific immune modulator and has been shown to have significant antitumor activity in vitro and in vivo in preclinical and some early clinical studies.
(Copovithane, NCI Thesaurus)
A biodegradable poly(ethylene glycol)-poly(D,L-lactide) copolymer micelle nanoparticle-entrapped formulation of paclitaxel with antineoplastic activity.
(Paclitaxel-loaded polymeric micelle, NCI Thesaurus)
The thermosensitive triblock copolymer component of this formulation transforms from a water-soluble polymer at room temperature to a water-insoluble, biodegradable gel depot at body temperature; intratumoral controlled-release of paclitaxel from the gel minimizes systemic exposure to paclitaxel and the paclitaxel toxicity profile.
(PGLA/PEG Copolymer-Based Paclitaxel, NCI Thesaurus)
Upon intratumoral injection, paclitaxel is released slowly and continuously into tumor tissues from the gelled thermosensitive triblock copolymer over a period of 4 to 6 weeks; in tumor cells, paclitaxel binds to tubulin and inhibits the disassembly-assembly dynamics of microtubules, resulting in cell cycle arrest and cell death.
(PGLA/PEG Copolymer-Based Paclitaxel, NCI Thesaurus)
