CTCAE Grade 3 Large Bowel Mucositis or Stomatitis by Clinical Examination Classification

Confluent ulcerations or pseudomembranes; bleeding with minor trauma (NCI Thesaurus/CTCAE)

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CTCAE Grade 3 Large Bowel Leak

Symptomatic and interfering with GI function; invasive or endoscopic intervention indicated

CTCAE Grade 3 Kidney Perforation

Symptomatic, operative intervention indicated

CTCAE Grade 3 Kidney Pain

Severe pain; pain or analgesics severely interfering with ADL

CTCAE Grade 3 Kidney Leak

Symptomatic, interfering with GU function; invasive or endoscopic intervention indicated

CTCAE Grade 3 Kidney Intra-Operative Injury

Complete resection or reconstruction of injured organ/structure indicated

CTCAE Grade 3 Kidney Infection with Unknown Absolute Neutrophil Count

IV antibiotic, antifungal, or antiviral intervention indicated; interventional radiology or operative intervention indicated