CTCAE Grade 4 Urinary Retention

Life-threatening consequences; organ failure (e.g., bladder rupture); operative intervention requiring organ resection indicated (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Urinary Incontinence

Operative intervention indicated (e.g., cystectomy or permanent urinary diversion)

CTCAE Grade 4 Urinary Hemorrhage NOS

Life-threatening consequences; major urgent intervention indicated

CTCAE Grade 4 Urinary Conduit Intra-Operative Injury

Life threatening consequences; disabling

CTCAE Grade 4 Urethra Stricture or Stenosis

Life-threatening consequences; organ failure or operative intervention requiring organ resection indicated

CTCAE Grade 4 Urethra Perforation

Life-threatening consequences or organ failure; operative intervention requiring organ resection indicated

CTCAE Grade 4 Urethra Pain