CTCAE Grade 4 Vulva Infection with Normal Absolute Neutrophil Count or Grade 1 or 2 Neutrophils

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis) (NCI Thesaurus/CTCAE)

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CTCAE Grade 4 Vulva Infection Documented Clinically or Microbiologically with Grade 3 or 4 Neutrophils

Life-threatening consequences (e.g., septic shock, hypotension, acidosis, necrosis)

CTCAE Grade 4 Vomiting

CTCAE Grade 4 Voice Changes and Dysarthria

Disabling; non-understandable voice or aphonic; requires voice aid (e.g., electrolarynx) for >50% of communication or requires >50% written communication

CTCAE Grade 4 Vital Capacity

<25% of predicted value

CTCAE Grade 4 Visceral Artery Injury

Life-threatening; disabling; evidence of end organ damage (e.g., stroke, MI, organ or limb loss)

CTCAE Grade 4 Viscera Vein Injury

Life-threatening; disabling; evidence of end organ damage