Health / Medical Topics

    Cyclooxygenase inhibitor

    Pronunciation

    Definition 1

    COX inhibitor. A type of drug that is used to treat inflammation and pain, and is being studied in the prevention and treatment of cancer. Cyclo-oxygenase inhibitors belong to the family of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Also called COX inhibitor. (NCI Dictionary)

    Definition 2

    Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including prostaglandins, prostacyclin and thromboxane, from arachidonic acid. Cyclooxygenase inhibitors are a type of non-steroidal anti-inflammatory drug. (NCI Thesaurus)

    Definition 3

    Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes. (NLM, Medical Subject Headings)




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