CYP11B2 wt Allele

Human CYP11B2 wild-type allele is located within 8q21-q22 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B2, mitochondrial protein, is involved in the synthesis of aldosterone and 18-oxocortisol. Functional mutations in the CYP11B2 gene are associated with congenital hypoaldosteronism, a disorder that is due to corticosterone methyloxidase type II deficiency. CYP11B1/CYP11B2 gene fusion causes glucocorticoid-remediable aldosteronism. (NCI Thesaurus)

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CYP11B2 Gene

This gene is involved in mineralocorticoid metabolism.

CYP11B1 wt Allele

Human CYP11B1 wild-type allele is located within 8q21 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B1,…

CYP11B1 Gene

This gene plays a role in the metabolism of glucucorticoids.

CYP11A1 wt Allele

Human CYP11A1 wild-type allele is located within 15q23-q24 and is approximately 30 kb in length. This allele, which encodes cytochrome P450 11A1,…

CYP11A1 Gene

This gene is involved in steroid metabolism.

Cynomolgus Monkey

A macaque, Macaca fascicularis (M. cynomolgus), found mostly in southeastern Asia, Borneo, and the Philippines.