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CYSTIC FIBROSIS
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The most common hereditary disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known
Synonyms:
CF; cystic fibrosis; fibrocystic disease of the pancreas; mucoviscidosis; pancreatic fibrosis
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("cystic fibrosis" is a kind of...):
monogenic disease; monogenic disorder (an inherited disease controlled by a single pair of genes)
fibrosis (development of excess fibrous connective tissue in an organ)
Context examples:
A spectrum of liver disorders that develop in patients with cystic fibrosis.
(Liver Disease Associated with Cystic Fibrosis, NCI Thesaurus)
The substance in jiang huang that gives it a yellow color (curcumin) is being studied in the treatment of cancer, Alzheimer disease, cystic fibrosis, and psoriasis.
(Jiang huang, NCI Dictionary)
In humans, this species is pathogenic and associated with cystic fibrosis.
(Burkholderia cenocepacia, NCI Thesaurus)
The defects in cAMP-regulated chloride channel CTFR are believed to be the major cause for cystic fibrosis.
(CFTR Pathway, NCI Thesaurus/BIOCARTA)
It holds special promise for a subset of patients, about 10 percent of the people with cystic fibrosis, who do not respond to any treatment.
(Scientists find new approach that shows promise for treating cystic fibrosis, National Institutes of Health)
Causes include allergic rhinitis, chronic sinusitis, and cystic fibrosis.
(Ethmoid Sinus Polyp, NCI Thesaurus)
A formulation of the synthetic monobactam antibiotic, aztreonam and lysine used in an inhaled form for the treatment of chronic airway infections by Pseudomonas aeruginosa in patients with cystic fibrosis.
(Aztreonam Lysine, NCI Thesaurus)
A drug given in an aerosol mist to decrease the thickness of mucus in the lungs of patients with cystic fibrosis.
(Dornase alfa inhalation solution, NCI Dictionary)
Cystic fibrosis transmembrane conductance regulator (1480 aa, ~168 kDa) is encoded by the human CFTR gene.
(Cystic Fibrosis Transmembrane Conductance Regulator, NCI Thesaurus)
An immune reaction to aspergillus in patients usually suffering from asthma or cystic fibrosis.
(Allergic Bronchopulmonary Aspergillosis, NCI Thesaurus)
