Library / English Dictionary

    CYTOSKELETON

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    A microscopic network of actin filaments and microtubules in the cytoplasm of many living cells that gives the cell shape and coherenceplay

    Classified under:

    Nouns denoting body parts

    Hypernyms ("cytoskeleton" is a kind of...):

    anatomical structure; bodily structure; body structure; complex body part; structure (a particular complex anatomical part of a living thing and its construction and arrangement)

    Holonyms ("cytoskeleton" is a part of...):

    cytol; cytoplasm (the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism)

    Credits

     Context examples: 

    Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin.

    (Microtubule, NCI Thesaurus/LocusLink)

    This gene plays a role in both cell adhesion and cytoskeleton modeling.

    (MSN Gene, NCI Thesaurus)

    This protein plays a role in both cell adhesion and connection of the cytoskeleton to the plasma membrane.

    (Moesin, NCI Thesaurus)

    Microfilaments physically associate with microtubules to play a structural role in cytoskeleton integrity.

    (Microfilament Protein, NCI Thesaurus)

    A fluid cytoplasmic substance filling the interstices of the cytoskeleton.

    (Cytoplasmic Matrix, NCI Thesaurus)

    This allele, which encodes moesin protein, is involved in the modulation both of cell-cell adhesion and the structure of the cytoskeleton.

    (MSN wt Allele, NCI Thesaurus)

    This protein plays a role in cytoskeleton rearrangement andmetastasis suppression.

    (Metastasis-Suppressor KiSS-1, NCI Thesaurus)

    Calpains digest the links between the actin cytoskeleton and several focal adhesion complex proteins; talin, paxillin and focal adhesion kinase.

    (Calpain-2 Cell Motility Pathway, NCI Thesaurus/BIOCARTA)

    The classical cadherins have five homologous extracellular domains and a cytosolic domain which binds through catenin to the cytoskeleton.

    (Cadherin, NCI Thesaurus)

    This allele, which encodes PDZ and LIM domain protein 4, may play a role in the modulation of the structure of the actin cytoskeleton.

    (PDLIM4 wt Allele, NCI Thesaurus)


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