Health / Medical Topics

    DARC wt Allele

    Human DARC wild-type allele is located within 1q21-q22 and is approximately 3 kb in length. This allele, which encodes Duffy antigen/chemokine receptor protein, plays a role in the mediation of cellular interactions with cytokines. Polymorphisms in the gene are the basis for the Duffy blood group types. (NCI Thesaurus)




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