DEAD/H Box Protein 1

Encoded by human DDX1 Gene and highly expressed in neuroectodermal tissues, 740-amino acid 82.4-kD DEAD/H Box Protein 1 has unknown function, contains a SPRY domain, and belongs to the DEAD/H box ATP-dependent RNA helicase family. DEAD box proteins, characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif, are putative RNA helicases that alter RNA secondary structure and influence translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on distribution, some family members may be involved in embryogenesis, spermatogenesis, and cellular growth and division. (from LocusLink, Swiss-Prot, OMIM, and NCI) (NCI Thesaurus)

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