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DEFECTIVE
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Not working properly
Example:
a defective appliance
Synonyms:
bad; defective
Classified under:
Similar:
malfunctioning; nonfunctional (not performing or able to perform its regular function)
Derivation:
defectiveness (the state of being defective)
Sense 2
Meaning:
Markedly subnormal in structure or function or intelligence or behavior
Example:
defective speech
Classified under:
Similar:
abnormal; unnatural (not normal; not typical or usual or regular or conforming to a norm)
Sense 3
Meaning:
Having a defect
Example:
I returned the appliance because it was defective
Synonyms:
defective; faulty
Classified under:
Adjectives
Similar:
imperfect (not perfect; defective or inadequate)
Derivation:
defectiveness (the state of being defective)
Context examples:
A replication-defective recombinant canarypox virus (ALVAC) that contains the entire human carcinoembryonic antigen (CEA) gene.
(ALVAC-CEA (VCP248), NCI Thesaurus)
A cancer vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) encoding the cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities.
(ALVAC-ESO-1 Vaccine, NCI Thesaurus)
A vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) that encodes the gene for human interleukin-12 (hIL-12).
(Canarypox-hIL-12 Melanoma Vaccine, NCI Thesaurus)
Genomic instability associated with defective DNA mismatch repair in tumors.
(Microsatellite instability, NCI Thesaurus)
A genetic disorder characterized by defective polymorphonuclear cell actin function, resulting in impaired granulocyte motility.
(Neutrophil Actin Defect, NCI Thesaurus)
Only the light chain (kappa or lambda) of the immunoglobulin is defective.
(Multiple Myeloma-Light Chain Only, NCI Thesaurus)
A group of usually autosomal dominant inherited disorders characterized by defective synthesis of collagen type I resulting in defective collagen formation.
(Osteogenesis Imperfecta, NCI Thesaurus)
This agent is more active against tumor cells that are defective in p53 function.
(Penclomedine, NCI Thesaurus)
The branch of surgery concerned with restoration, reconstruction, or improvement of defective, damaged, or missing structures.
(Plastic surgery, NCI Thesaurus)
The heavy chain, IgM, of the immunoglobulin is defective.
(Multiple Myeloma-IgM (not Waldenstrom Macroglobulinemia), NCI Thesaurus)
