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DEGENERATIVE
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
(of illness) marked by gradual deterioration of organs and cells along with loss of function
Example:
degenerative diseases of old age
Classified under:
Similar:
chronic (being long-lasting and recurrent or characterized by long suffering)
Derivation:
degenerate (grow worse)
Context examples:
Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age.
(Hip Osteoarthritis, NLM, Medical Subject Headings)
Disruptions in this process can result in inviability, premature aging and predisposition to cancers and degenerative diseases.
(Homologous Recombination, NCI Thesaurus)
Appreciating this complexity is important for guiding the development of therapies that target the complement immune system to treat degenerative diseases of the retina.
(Immune system can slow degenerative eye disease, National Institutes of Health)
Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others.
(Oxidative stress, NCI Thesaurus)
A rare disorder characterized by degenerative changes in the limbic area of the brain.
(Limbic Encephalitis, NCI Thesaurus)
A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus.
(Parkinson's Disease, NCI Thesaurus)
Osteoarthritis tends to occur later in life and has been largely considered as a degenerative disorder in which pain is produced by damage and wear and tear to bone and cartilage.
(Joint lubricating fluid plays key role in osteoarthritic pain, University of Cambridge)
Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents’ lives.
(Experimental treatment slows prion disease, extends life of mice, National Institutes of Health)
Prion diseases are slow degenerative diseases of the central nervous system that occur in people and various other mammals.
(Retinal prion disease study redefines role for brain cells, National Institutes of Health)
Acceleration of aging may actually be part of the mechanism by which degenerative disease disrupts the structure and function of the brain.
(NIH scientists search for the clocks behind aging brain disorders, National Institutes of Health)
