Deletion Mutation

Definition 1

Any rearrangement to the genomic content that results in the loss of one or more nucleotides of DNA. Deletions are generally irreversible rearrangements. They may alter the reading frame of a gene, or may result in loss of large chromosomal regions. (NCI Thesaurus)

Definition 2

Absence of a segment of DNA; may be as small as a single base or as large as a whole chromosome. (NCI Dictionary)

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Deletion

Elimination, especially by blotting out, cutting out, or erasing.

Deleterious Mutation

A mutation that is documented to be associated with risk of disease.