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DEOXYRIBOSE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A sugar that is a constituent of nucleic acids
Classified under:
Hypernyms ("deoxyribose" is a kind of...):
carbohydrate; saccharide; sugar (an essential structural component of living cells and source of energy for animals; includes simple sugars with small molecules as well as macromolecular substances; are classified according to the number of monosaccharide groups they contain)
Context examples:
A subunit of DNA or RNA consisting of a nitrogenous base (adenine, guanine, thymine, or cytosine in DNA; adenine, guanine, uracil, or cytosine in RNA), a phosphate molecule, and a sugar molecule (deoxyribose in DNA and ribose in RNA).
(Nucleotide, NCI Thesaurus)
DNA Synthesis Induction consists of the initiation of activities involved in the polymeric linkage of deoxyribose moieties (with adenine, guanine, cytosine, or thymine side chains) by phosphate groups attached to their 5-prime and 3-prime sugar hydroxyls.
(DNA Synthesis Induction, NCI Thesaurus)
Depurination involves cleavage of the N-glycosidic link between a purine base and the remaining deoxyribose portion of the effected nucleotide in DNA, leading to loss of the purine base while leaving the DNA backbone intact.
(Depurination, NCI Thesaurus)
DNA Synthesis Inhibition involves interference with, or restraint of, the activities involved in the polymeric linkage of deoxyribose moieties (with adenine, guanine, cytosine, or thymine side chains) by phosphate groups attached to their 5-prime and 3-prime sugar hydroxyls.
(DNA Synthesis Inhibition, NCI Thesaurus)
After cycloaromatization, the enediyne core of these antibiotics is converted to a benzene diradical intermediate that removes hydrogens from deoxyriboses along the minor groove of DNA, resulting in single- and double-strand breaks and apoptosis.
(Enediyne Antineoplastic Antibiotic, NCI Thesaurus)
